‘I’m deeply uncomfortable’: Anthropic CEO warns that a cadre of AI leaders, including himself, should not be in charge of the technology’s future

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Anthropic CEO Dario Amodei doesn’t think he should be the one calling the shots on the guardrails surrounding AI.

In an interview with Anderson Cooper on CBS News’ 60 Minutes that aired in November 2025, the CEO said AI should be more heavily regulated, with fewer decisions about the future of the technology left to just the heads of big tech companies.

“I think I’m deeply uncomfortable with these decisions being made by a few companies, by a few people,” Amodei said. “And this is one reason why I’ve always advocated for responsible and thoughtful regulation of the technology.”

“Who elected you and Sam Altman?” Cooper asked.

“No one. Honestly, no one,” Amodei replied.

Anthropic has adopted the philosophy of being transparent about the limitations—and dangers—of AI as it continues to develop, he added. Ahead of the interview’s release, the company said it had thwarted “the first documented case of a large-scale AI cyberattack executed without substantial human intervention.” 

Anthropic said last week it had donated $20 million to Public First Action, a super PAC focused on AI safety and regulation—and one that directly opposed super PAC...

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